BACKGROUND: aminophylline is widely used to reverse dipyridamole-related adverse effects during stress myocardial perfusion imaging (MPI).
METHODS: 2,250 consecutive patients were evaluated.
RESULTS: No severe adverse events were observed. Low-dose (25 mg) aminophylline relieved symptoms in 98.8% of patients with mild adverse events. An additional 25 mg aminophylline reversed the moderate adverse events.
CONCLUSION: aminophylline at 25 mg IV is sufficient to relieve nearly all dipyridamole-related adverse events observed during stress MPI.
J Nucl Cardiol. 2014 Mar 14